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 Welcome, AI enthusiasts.

Microsoft’s coding platform GitHub just welcomed rivals Anthropic and Google to the party — and OpenAI isn’t the only fish in the sea anymore.

Is the move a sign of shifting alliances or a glimpse at a multi-model future for the best user experiences? Let’s get into it…

In today’s issue:

• GitHub and Microsoft open Copilot to rival AI models

• OpenAI plans first custom AI chip

• Create a custom AI voice with a text prompt

• New AI model predicts early drug development

• 6 new AI tools & Tools on sale

• New AI Job Opportunities

Read time: 4 minutes

MICROSOFT

🛠️ GitHub and Microsoft open Copilot to rival AI models

The Rundown: Microsoft's GitHub just announced that it is expanding its AI coding assistant to include models from Anthropic and Google, alongside a series of new updates and features to the platform — breaking from the company’s traditional OpenAI exclusivity.

The details:

• The platform will allow developers to switch between assistants, including Claude and Gemini, although OpenAI's models remain the default choice.

• GitHub also introduced Spark, a new feature that allows users to build applications with natural language prompts.

• The platform announced features including multi-file editing, Copilot code reviews, new agentic updates to Workspaces, and Apple Xcode support.

• GitHub's decision to embrace multiple AI providers comes as its Copilot service reaches a major milestone with over a million paying subscribers.

Why it matters: While some may point to even more smoke from the Microsoft-OpenAI relationship, this move may simply acknowledge that different models excel at different tasks. If GitHub prioritizes giving users the best developer experience, having model choice is a no-brainer — even if it ruffles exclusivity feathers.

OPENAI

🤝 OpenAI plans first custom AI chip

The Rundown: OpenAI is developing its first custom semiconductor with Broadcom and TSMC while expanding its chip supplier base to include AMD alongside NVIDIA, according to a new report from Reuters.

The details:

• OpenAI has reportedly assembled a team of about 20 engineers, including former Google TPU designers, to develop an AI chip targeted for 2026.

• After initially exploring options to build its own chip factories, OpenAI is instead opting to partner with Broadcom for design and TSMC for manufacturing.

• The company also plans to add AMD's new MI300X processors to its training infrastructure, reducing reliance on Nvidia's GPUs.

• The moves come as OpenAI faces mounting compute costs, with reports suggesting the company could lose $5B this year despite $3.7B in revenue.

Why it matters: The AI boom drives unprecedented demand for specialized chips, forcing industry leaders to rethink their hardware strategies. Scaling compute power is the key to unlocking more powerful AI — and the race may be won or lost on hardware strategy rather than just model capabilities.

AI TRAINING

🎙️ Create a custom AI voice with a text prompt

The Rundown: ElevenLabs’ new Voice Design feature allows you to create unique AI voices on demand with natural accents, emotions, and speaking styles for your creative projects.

Step-by-step:

1. Head over to Eleven Labs and choose “Voices” in the left sidebar.

2. Select "Voice Design" from the Add new voice option.

3. Write a detailed voice description including age, accent, gender, and style.

4. Preview three AI-generated variations, select your favorite, and give it a name for immediate use.

Pro tip: Check out ElevenLabs prompting guide for more details on producing the best possible voices from Voice Design and sample prompts to help you get started.

IAMBIC AI

🧬 New AI model predicts early drug development

The Rundown: Biotech startup Iambic Therapeutics just revealed Enchant, an AI platform designed to predict how drug candidates perform in human trials before leaving the lab.

The details:

• The multimodal AI system combines extensive laboratory data with limited clinical information to predict a drug's potential success early.

• Enchant sets new accuracy marks for predicting human drug interactions, achieving a 74% correlation compared to the previous 58% SOTA score.

• The technology can begin making reliable predictions after studying five drug molecules, requiring minimal human trial data to generate insights.

• Enchant processes multiple types of research data simultaneously, helping bridge the gap between laboratory findings and clinical outcomes.

Why it matters: One of healthcare's biggest challenges is the massive failure rate of drugs during human trials, despite years of promising lab results. By cutting development timelines and identifying issues earlier, Iambic’s AI can reshape how new medicines reach patients — while reducing the billions spent bringing drugs to market.

Prompt of today

Prompts:

At night, the round moon hangs in the sky. In Chinese mythology, the Cowherd and Weaver Girl, a boy wearing Hanfu and a girl wearing white Hanfu and a gorgeous headdress, face to face, holding hands tightly together. The two of them stand on a bridge made up of many pigeons in the sky, surrounded by white clouds. In the distance, there are ancient Chinese towers, like palaces in the sky,Full Length Shot,full body shot, highly detailed,photography,beautiful cinematic lighting --stylize 950 --personalize --v 6.1

Tools showcase

• 📓 Magic Notepad by TimeOS - Turn notes and meeting transcriptions into structured insights, beautiful formatting, and next steps.

• 🐴 Lasso AI - Turn metadata into revenue with additive, verified contact data via industry-leading index accuracy

• 📊 Aptitude - End-to-end customer research platform that uses AI-moderated interviews for deep insights

• 🧠 Inncivio - Learn anything faster with a personalized AI micro-learning platform

• 🤓 Sourcely - AI-powered literature sourcing tool to streamline research for academics

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Tools on sale

• 🏷️88%Off mavic: mavic is your business's AI brand marketer for strategy, ideation, content creation and publishing

• 🏷️82%Off Socrates: Instant Answers from your private files on Win, Mac, or web

• 🏷️53%Off Taja: Taja allows you to publish YouTube content 10x faster by creating everything you need in 8 minutes

• 🏷️90%Off Emailpref: Let users choose their subscription preferences and sync data across platforms

• 🏷️62%Off Butternut AI: SUse this AI platform to build your dream website in seconds with prompts—without any coding

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New AI Job Opportunities

• 📈 The Rundown - Partnerships Manager (University)

• 🛡️ Weights & Biases - Security Engineering Analyst

• 📊 Glean - Product Manager

• 🔬 Contextual AI - Research Intern (Winter)

• 🏛️ Palantir Technologies - Capture Strategist (US Government)

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AI around the world

Elon Musk predicted at the Future Investment Initiative conference that by 2040, there will be at least 10B humanoid robots priced between $20 and $25K.

Amazon expanded the company’s Rufus AI shopping assistant in beta to European markets, offering personalized product recommendations and comparison capabilities through conversational interactions in the mobile app.

OpenAI launched new search capabilities for ChatGPT history, allowing users to easily reference, navigate, or revisit old conversations.

Elon Musk’s xAI is reportedly seeking a new funding round that would value the AI startup at $40B, a significant jump from its $24B valuation following a raise in May.

Google CEO Sundar Pichai revealed that the company’s multimodal, agentic smartphone app Project Astra, which was demoed at Google I/O, is expected to be available ‘as early as 2025.’

Actor Robert Downey Jr. criticized the use of AI digital replicas in Hollywood, saying he ‘intends to sue all future executives that recreate his likeness,’ even after his death.

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